Radiprodil pediatric formulation development

Radiprodil is currently under development for the treatment of Infantile Spasm (IS), a rare and catastrophic seizure disorder that occurs in young children. In this perspective, a suitable formulation purposely designed for the treatment of the target paediatric population infants from 2 to 14 months was developed taking into account the ideal attributes of a paediatric formulation (i.e. to grant flexible dosage increments in an accurate way; to allow compliance; to be palatable; safe and easy to administer; with minimum excipients and stable). The key challenges faced during development are herein presented and discussed.

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Radiprodil pediatric formulation development

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