How to understand the key challenges and issues of a compound, and develop a plan to eliminate them

Recently presented at SOT 2018 by our expert, Sergio Raimondo, this scientific presentation discusses the developabilities properties of a new candidate, what impact this will have on project timelines, de-risking strategies and examples of case studies.

Sergio focuses on the following areas in this educational presentation -

  • Understanding the developability properties of the candidate drug to improve success
    • Developability/scalability of route of synthesis
    • Salt/polymorph selection, solubility in different media and permeability
    • BCS classification, challenges in development for BCS class 2 and 4 compounds
    • On target and off target toxicity
    • Early safety screens tailored for the specific target/class of compound
  • Merging efficacy and PK/PD data with developability endpoints to meet the target product profile

Get your copy now and discover more about the key challenges of a compound and how you can develop a plan to eliminate them.

How to understand the key challenges and issues of a compound, and develop a plan to eliminate them

Get your copy today!

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