Aptuit | Integrated CMC | Pre- and formulation development

Formulation development

The expertise essential to effective experimentation

Our formulation development team is staffed by scientists with a wealth of expertise and experience in the pharmaceutical development field, in particular in the development of oral solid dosage forms as well as Dry Powder Inhaled (DPI) dosage forms.

Aptuit | Formulation development

Our expertise spans the whole spectrum of product development; delivering effective solutions for each development phase, from preclinical stages up to the development of drug products, and Investigational Medicinal Products (IMPs) to be tested in different clinical studies from Phase I to IV. Our formulation techniques allow us to support development of drugs over the entire Biopharmaceutical Classification System (BCS) range.

Our team has extensive experience in the use of more conventional technological approaches, such as tabletting and capsule filling, as well as the most advanced enabling ones, such as Hot Melt Extrusion, Spray Drying, Nanomilling (by Wet Beads Milling), Lipidic Formulations including Self-Emulsifying Drug Delivery Systems (SEDDS) and Self-Micro Emulsifying Drug Delivery Systems (SMEDDS).

In addition, we have strong and consolidated experience in the use of QbD / DoE approach, allowing the development of robust formulations and processes enabling their transfer to the selected commercial manufacturing sites.