Aptuit offers a one-stop-shop for Drug Discovery characterized by a highly integrated process approach, with co-located expertise and state-of-the-art equipments and technologies. High quality results are granted by a combined and dedicated effort of multidisciplinary teams, and our analytical experts can provide support to your Drug Discovery effort through the whole process, from target validation to lead optimization and to candidate profiling.

Our advanced technologies and expert scientists have proven track record in structural elucidation of small and medium Mw molecules, in method development and in purification.

Our staff is committed to providing the highest quality analytical and research services, by means of all the spectroscopic techniques (NMR, IR and MS) and separation technologies.

Our Drug Discovery support services include:

• Structural ID, characterization and purity evaluation of tool molecules, hits and leads
• Support during synthesis of new chemical entities (NCEs)
• Kinetics and reaction monitoring (including analytical technologies for parallel synthesis monitoring)
• Structural elucidation with data acquisition (multiple analytical techniques) and expert interpretation for full structural ID and characterization
• Complete certificate of analysis and/or purification of New chemical Entities
• Customized analytic method (NMR or HPLC) set up and transferred to the customer
• Analytical technologies for parallel synthesis
• Conformational studies in solution
• Unknown structure characterization
• Ligand- target interaction studies for support to structure- and ligand-based drug design
• Stereochemical assessment; enantiomers separation; enantiomeric excess determination