Discovery Pharmacology can support all phases of the Drug Discovery process from Target Validation to Candidate Selection and beyond, in a fully integrated manner with other preclinical disciplines. However, the individual packages of pharmacological services can be offered both based on a specific phase of the process (e.g. Target Validation, Hit Generation, Lead Characterization etc.) and through specific assays or tests (selectivity panel, mode of action studies, receptor occupancy, behavioral tests etc.).
We have significant expertise gained from our experience in pharmaceutical and contract research industries, as well as academia, and produce high quality data and reports on which strategic development decisions may be confidently based. Studies are designed to suit individual compounds under evaluation and to accommodate clients specific requirements.
At Aptuit, we are committed to therapeutic area specialization. Our Discovery Pharmacology services are used to screen compounds for lead/candidate selection and to test pharmacological efficacy in a range of specialist in vitro and in vivo pharmacological disease models covering respiratory and inflammation, the central nervous system (CNS), oncolgy, cardiovascular system and infectious disease.
Our Discovery Pharmacology services include:
- Molecular & Cellular Biology
- Electrophysiology
- In vitro Pharmacology
- In vivo Pharmacology
- Translational Biology
- Safety Pharmacology